Product Critical Technical Advantages
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Remote Architecture for Cleanroom Safety: The 500 series transmitter can be mounted up to 300 meters away from the sensor. This allows the sensitive electronics to be located in a non-sterile service area while the sensor operates within the cleanroom or sterile core, reducing the risk of contamination during maintenance.
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Highest Material Compliance and Purity: Featuring an electropolished measuring tube made of 1.4435 (316L) stainless steel with low delta ferrite, the Promass P meets the stringent ASME BPE, 3-A, and EHEDG standards. This specialized construction prevents product contamination and ensures high resistance to the aggressive chemicals used in sterilization.
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Rapid Recovery from CIP/SIP Cycles: The sensor is engineered to withstand the extreme thermal shocks of Cleaning-in-Place and Sterilization-in-Place. Unlike standard flowmeters, the Promass P recovers its measurement stability almost instantly after a cycle, allowing for faster batch transitions and higher throughput.
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Heartbeat Technology for Regulatory Compliance: This integrated diagnostic suite provides continuous monitoring and documented verification without interrupting the sterile process. It enables operators to prove that the device is performing within specification, which is essential for maintaining validated pharmaceutical processes.
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Advanced Connectivity and I/O Flexibility: The Proline 500 transmitter provides up to 4 freely combinable I/Os and supports modern industrial protocols like EtherNet/IP and PROFINET. With a built-in web server and WLAN access, technicians can configure the device wirelessly, avoiding physical contact with the hardware in sensitive environments.
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Multivariable Precision without Pipe Constraints: By measuring mass flow, density, and temperature simultaneously, the Promass P 500 reduces the number of penetrations required in sterile piping. Its ability to measure accurately without straight inlet or outlet runs allows it to fit perfectly into compact, modular biotech skids.
Key Device Specifications
| Feature | Technical Specification |
| Nominal Diameter | DN 8 to 50 (3/8 to 2″) |
| Wetted Materials | 1.4435 (316L) stainless steel, low delta ferrite |
| Surface Finish | Electropolished Ra max 0.38 µm or 0.76 µm |
| Installation Type | Remote version (standard cable up to 300m) |
| Connectivity | Ethernet/IP, PROFINET, Modbus RS485, WLAN |
| Certifications | ASME BPE, 3-A, EHEDG, SIL 2/3, Pharma-specific |
Field of Application
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Biotech Production: Ideal for the precise dosing and transfer of cell culture media, buffers, and active pharmaceutical ingredients (APIs).
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Sterile Filling Lines: High-accuracy mass flow measurement for the filling of vaccines, biologics, and other high-value sterile liquids.
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Chromatography & Filtration: Monitoring flow and density in downstream processing units where cleanability and material integrity are critical.
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Hygienic Food Production: Applied in high-purity food processes such as infant formula or liquid vitamin production requiring maximum safety.




